Atopic dermatitis pathophysiology and therapeutic targeting of the aryl hydrocarbon receptor

Lessons learned from keratinocytes, inflammatory cytokines and microbiota

Gijs Rikken • Boek • paperback

• Samenvatting
  Free download at https://doi.org/10.54195/9789465150673
  The general aim of my thesis was to investigate the disease mechanisms by which epidermal keratinocytes drive or contribute to AD pathology by exploring interactions between keratinocytes, immune mediators and microbiota and how these can be targeted by
  therapeutics in preclinical organotypic skin models. The following key objectives were defined to meet my thesis aim:
  1. To develop organotypic epidermal equivalents to study inflammatory skin diseases.
  2. To study the therapeutic spectrum and disease-modulating effects of aryl hydrocarbon receptor ligands.
  3. To investigate host-microbe interactions important for skin health and in disease.
• Productinformatie
  Binding : Paperback
  Distributievorm : Boek (print, druk)
  Formaat : 170mm x 240mm
  Aantal pagina's : 405
  Uitgeverij : Radboud University Press
  ISBN : 9789465150673
  Datum publicatie : 07-2025
  
• Inhoudsopgave
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